Simply put, they proposed that to be sweet, a compound must contain a hydrogen bond donor AH and a Lewis base B separated by about 0.
According to this theory, the AH-B unit of a sweetener binds with a corresponding AH-B unit on the biological sweetness receptor to produce the sensation of sweetness. B-X theory proposed by Lemont Kier in While previous researchers had noted that among some groups of compounds, there seemed to be a correlation between hydrophobicity and sweetness, this theory formalized these observations by proposing that to be sweet, a compound must have a third binding site labeled X that could interact with a hydrophobic site on the sweetness receptor via London dispersion forces.
Later researchers have statistically analyzed the distances between the presumed AH, B, and X sites in several families of sweet substances to estimate the distances between these interaction sites on the sweetness receptor. This theory involves a total of eight interaction sites between a sweetener and the sweetness receptor, although not all sweeteners interact with all eight sites. The most potent of these, lugdunameis abouttimes sweeter than sucrose.
From Wikipedia, the free encyclopedia. Redirected from Sweeter. For other uses, see Sweet disambiguationSweetness disambiguationand Sweetening disambiguation. Further information: Sugar substitute. Twin Res Hum Genet. Opioids, sweets and a mechanism for positive affect: Broad motivational implications. DobbingSweat Tastes Sweeter - The Beyond (3) - Chasm (Cassette, Album). Journal of Comparative and Physiological Psychology. The New England Journal of Medicine.
The Body Almanac: Mind-boggling facts about today's human body and high-tech medicine. New York: Doubleday. American Scientist. Tucson: University of Arizona Press. The Psychology of Eating and Drinking. New York: W. The Cambridge Encyclopedia of Human Evolution. Cambridge: Cambridge University Press. Social Science Information. Attitudes towards sugar and sweetness in historical and social perspective. Scientific American. Bibcode : SciAm. Textbook of Medical Physiology 8th Album).
Philadelphia: W. Eric; Schiffman, Susan S. Thomas; Brands, Linda M. Eric; Orthoefer, Frank T. Organic Chemistry 4th ed. Proceedings of the Oklahoma Academy of Science. The World of Chemistry: Essentials 4th ed. Retrieved 14 September Guyton and Hall Textbook of Medical Physiology 11th ed. Philadelphia: Elsevier Saunders. N Engl J Med. Crit Rev Food Sci Nutr. Bibcode : Sci Archived from the original on Bibcode : PNAS The Journal of Physiological Sciences.
Chemical Senses. Archived from the original on March 19, Retrieved July 28, The Journal of Cell Biology. Nature Communications. Bibcode : NatCo The Journal of Physiology. Bibcode : Natur. Bibcode : PNAS. Journal of Food Science. Berry Sweet. Berry Sweet Episode 6 Bursting with flavor, these recipes are bound to satisfy any sweet tooth! Ultimate Indulgence. Ultimate Indulgence Episode 7 Indulge yourself with these delectable treats!
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